INSULIN ASPART+INSULIN ASPART PROTAMINE

INSULIN ASPART+INSULIN ASPART PROTAMINE is for subcutaneous (under the skin) use only and should never be administered intravenously (IV) or in the veins. If you are changing the insulin brand or need to inject your insulin by another method, it should be done under strict medical supervision. Cases of heart failure have been reported when pioglitazone was used with insulin, especially in patients at high risk of cardiac heart failure. The first hyperglycemia symptoms (high blood sugar level) may include excessive thirst, dry mouth, increased frequency of urination, nausea, vomiting, drowsiness, flushed dry skin, loss of appetite, and acetone odour of the breath. You should closely monitor these symptoms. Symptoms like heart failure, weight gain and oedema (fluid deposition in tissue) should not be overruled. It is advisable not to consume alcohol as it may increase or decrease your blood glucose level. Care should be taken while travelling across more than two time zones. Your doctor may adjust your insulin schedule. INSULIN ASPART+INSULIN ASPART PROTAMINE may decrease the level of potassium, leading to a state of hypokalaemia that, if left untreated, may lead to respiratory paralysis, irregular heartbeat rhythm, coma, and even death. Do not take INSULIN ASPART+INSULIN ASPART PROTAMINE if you have any low blood glucose levels, kidney, liver, or heart problems, or problems with alcohol or other prescription recreational drugs. 

Drug-Drug Interaction: INSULIN ASPART+INSULIN ASPART PROTAMINE may have an interaction with bleeding disorder drugs (octreotide), antibiotics (isoniazid, ciprofloxacin, gatifloxacin), blood pressure-lowering pills (metoprolol), lipid-lowering pills (reserpine, niacin, clonidine, fenofibrate, guanethidine), pain killers (aspirin), antidiabetic (pramlintide, pioglitazone), anti-asthmatics (albuterol, epinephrine, terbutaline).

Drug-Food Interaction: INSULIN ASPART+INSULIN ASPART PROTAMINE may interact with an ayurvedic, homoeopathy, Unani, herbal supplements, or OTC items. Tell your doctor if you are using these products. Try to avoid the intake of alcoholic beverages with INSULIN ASPART+INSULIN ASPART PROTAMINE as it may increase or decrease your blood sugar level.

Drug-Disease Interaction: INSULIN ASPART+INSULIN ASPART PROTAMINE should not be given to patients with kidney disease, liver disease, low blood sugar/glucose level (hypoglycaemia), and low potassium level (hypokalaemia).

• Exercise may lower your body’s need for insulin during and for some time after the physical activity.

• Exercise may also speed up the effect of an insulin dose, especially if the exercise involves the area of injection site (for example, the leg should not be used for injection just prior to running).

• Discuss with your doctor how you should adjust your insulin regimen to accommodate exercise. 

• Avoid eating sugar food and prefer food cooked food low in calories.

• When traveling across more than 2 time zones, you should talk to your doctor concerning adjustments in your insulin schedule.

• You should undergo a test called the HbA1C (A1C) every 2-3 months for closely monitoring your blood sugar level while taking INSULIN ASPART+INSULIN ASPART PROTAMINE. 

• While using INSULIN ASPART+INSULIN ASPART PROTAMINE your blood sugar level might dip, which can result in seizure or unconsciousness, you should carry a quick source of sugar (glucose tablets or sugar candies) with you if you have symptoms of low blood sugar. 

• Discard the used insulin pen after 14 days, even if there is slight insulin left in it.

• Your doctor may tell you to have a regular potassium level as prolonged administration causes a life-threatening hypokalemia condition (low potassium).